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How to administer {{tdata('FFP fullname}} echo " ("; getdata('FFP name'); echo ")";?> - Quick Guide
Presentation
- {{tdata('FFP fullname}} echo " ("; getdata('FFP name'); echo ")";?>: 180-340mL
- Paediatric FFP: 45-90mL (4 doses can be obtained from a single donation)
- Please note that some blood banks in New Zealand are using FFP (24 hour shelflife) and some are using FFP-EL (120 hour shelflife).
Blood banks using FFP-EL are: Auckland, Christchurch, Dunedin, MidCentral, Middlemore, Tauranga, Waikato, Wellington.
![mg src="./images/ffp.jpg" alt="A unit of FFP" title="A unit of FFP" width="200" ](mg src="./images/ffp.jpg" alt="A unit of FFP" title="A unit of FFP" width="200" )
<?php
if (checkdata('FFP name')=='FFP-EL') {
echo '![./images/ELP.Flyer.2017.png" alt="Extended life FFP flyer (click here)" title="Extended life FFP flyer (click here)" width="200" ](./images/ELP.Flyer.2017.png" alt="Extended life FFP flyer (click here)" title="Extended life FFP flyer (click here)" width="200" )
Extended life FFP flyer';
echo '
';
echo '![./images/ELP.explanation.2017.png" alt="Extended life FFP explanation (click here)" title="Extended life FFP explanation (click here)" width="200" ](./images/ELP.explanation.2017.png" alt="Extended life FFP explanation (click here)" title="Extended life FFP explanation (click here)" width="200" )
Extended life FFP explained';
}
?>
ABO & RhD Compatibility
ABO
- Plasma components should be ABO compatible as follows:
- a group O patient can receive {{tdata('FFP name} of any ABO group
- a group A patient can receive A or AB {{tdata('FFP name}
- a group B patient can receive B or AB {{tdata('FFP name}
- a group AB patient can receive only AB {{tdata('FFP name}
- an unknown group patient can receive only AB or low titre group A {{tdata('FFP name}
- Emergency {{tdata('FFP name} is supplied as AB or low-titre A
Rh(D)
- No anti-D immunoglobulin need be given if Rh(D) negative patients receive Rh(D) positive {{tdata('FFP name} or cryoprecipitate.
- Although frozen plasma components may contain small amounts of red cell stroma, sensitisation following transfusion of Rh(D) positive units is most unlikely, as stroma is less immunogenic than intact red cells.
Therefore Cryoprecipitate of any Rh(D) type may be given regardless of the Rh(D) type of the recipient. Contact Blood Bank if you are not sure.
Storage
-
{{tdata('FFP name}} echo " ("; getdata('FFP shelflife'); echo ")";?>, once thawed, must be stored in an appropriately monitored (2-6°C) blood refrigerator according to Blood Bank standards for up to {{tdata('FFP shelflife} hours.
- Never store in a drug or food fridge.
- If the transfusion can not be started within 30 minutes, return the component to a blood refrigerator Bank immediately for appropriate storage.
- Blood Bank will only accept the unit back into stock if returned within 30 minutes of issue from Blood Bank.
- Once issued, {{tdata('FFP fullname} should be transfused as soon as possible.
Filter
- Use a standard blood infusion set which has a 170-200 micron
filter
- {{tdata('infusion set policy}
- All fresh components, including {{tdata('FFP fullname} , are leucodepleted
at source by NZBS. No bedside leucodepletion is necessary.
Pump
- Approved infusion pump devices may be used.
Rate and Duration
- Paediatrics:
- in a non-bleeding patient: infuse at 10-20mL/kg/hr
- resuscitation: rapid infusion based on the patient's haemodynamics
- Adults:
- in a non-bleeding patient: most adults will tolerate one unit of {{tdata('FFP name} every 90 minutes. Consider a slower rate in patients with or at risk of congestive cardiac failure.
- resuscitation: rapid infusion based on the patient's haemodynamics
- Infusion of all components should be completed within 4 hours of leaving refrigerated storage.
-
DO NOT
- DO NOT add medication to {{tdata('FFP name} or Cryoprecipitate
- DO NOT use 5% Dextrose solutions (may induce haemolysis)
- DO NOT use Lactated Ringer's or other balanced salt solutions that contain Calcium, as this may
induce clot formation in the blood bag and / or administration set.
Dose
- The standard therapeutic dose for {{tdata('FFP fullname} is 12-15mL per kg bodyweight.
- For paediatric patients, the dose should be written in mL, not units.
- See also [ASTH warfarin reversal guidelines (2013)](./documents/Warfarin reversal MJA 2013.pdf") and Prothrombinex on Clotting Factors page.
Dose Calculator
More Info